Functional Properties of Subretinal Transplants in Rabbit
نویسندگان
چکیده
منابع مشابه
Functional Properties of Subretinal Transplants in Rabbit
281 There has been a rapid growth in research focused on retinal transplantation as a strategy for restoration of or rescue of function in retinas rendered afunctional by disease or trauma. This strategy has been partially stimulated by recent transplantation efforts in brain related to neurodegenerative diseases such as Parkinson's, Huntington's, and Alzheimer's. These latter efforts have been...
متن کاملAdult rabbit retinal transplants.
PURPOSE To study the survival of adult retinal grafts prepared in a physiologically optimized way. METHODS Twenty-three rabbits received an adult full-thickness rabbit retinal transplant positioned under the host retina, using a vitrectomy technique. The transplants were prepared using a procedure based on a previously described in vitro model used for physiological experiments on the adult r...
متن کاملDirect activation and temporal response properties of rabbit retinal ganglion cells following subretinal stimulation.
In the last decade several groups have been developing vision prostheses to restore visual perception to the profoundly blind. Despite some promising results from human trials, further understanding of the neural mechanisms involved is crucial for improving the efficacy of these devices. One of the techniques involves placing stimulating electrodes in the subretinal space between the photorecep...
متن کاملNew Directions for Rabbit Antithymocyte Globulin (Thymoglobulin®) in Solid Organ Transplants, Stem Cell Transplants and Autoimmunity
In the 30 years since the rabbit antithymocyte globulin (rATG) Thymoglobulin(®) was first licensed, its use in solid organ transplantation and hematology has expanded progressively. Although the evidence base is incomplete, specific roles for rATG in organ transplant recipients using contemporary dosing strategies are now relatively well-identified. The addition of rATG induction to a standard ...
متن کاملSubretinal neovascularization after naphthalene damage to the rabbit retina.
PURPOSE To examine the retinotoxic effect of naphthalene, a powerful oxidative agent and a well-known cataractogenic agent. METHODS A 10% solution of naphthalene dissolved in paraffin oil was given every other day by gavage to 31 pigmented rabbits for 5 weeks, at a dose of 1 g/kg body weight. Four rabbits who received only paraffin oil served as controls. The eyes were clinically followed up ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neural Transplantation and Plasticity
سال: 1992
ISSN: 0792-8483
DOI: 10.1155/np.1992.281